Quetiapine fumarate, commonly known as Seroquel, is a type of antipsychotic medication indicated for the treatment of schizophrenia and bipolar disorder [
]. It exerts its action by binding to and modulating the neurotransmitter serotonin in the brain [
,
Seroquel is available as a generic drug in a tablet form [
Quetiapine fumarate is a synthetic analog of the human antipsychotic drug, quetiapine. Quetiapine was developed and synthesized to reduce and/or eliminate the influence of sodium and chloride ions on the pharmacodynamics of quetiapine [
Seroquel is marketed under several trade names, including Quetiapine, Seroquel, Seroquel SR, Seroquel SR, Seroquel XR, and Seroquel XR [
Quetiapine has been approved by the U. S. Food and Drug Administration (FDA) for the treatment of schizophrenia and the acute manic episodes associated with bipolar disorder [
The main pharmacokinetic characteristics of quetiapine are a relatively high oral bioavailability and a relatively short half-life. Therefore, the pharmacokinetic parameters of quetiapine in healthy volunteers and patients with hepatic and renal impairment are also affected by changes in pharmacokinetic parameters [
Seroquel is metabolized in the liver predominantly by cytochrome P450 (CYP) isoforms 3A4 (major route) and 2C9 (minor route) and is responsible for its accumulation and clearance [
Seroquel is also metabolized to an inactive metabolite after the liver clearance is reduced [
Seroquel pharmacokinetic model was validated in a pilot study on patients with major depressive disorder (MDD), generalized anxiety disorder (GAD), and panic disorder [
In the study, the area under the curve (AUC) and the serum concentration-time profiles of quetiapine in patients with MDD, GAD, and PD were significantly different than those in healthy controls. In addition, the AUC and the serum concentration-time profiles of quetiapine in patients with PD were significantly different than those in healthy controls. The terminal half-life of quetiapine (time-to-peak) and its plasma concentration (C
max) were estimated to be 2.9 and 2.6 hours, respectively. Quetiapine was less likely to be metabolized to a terminal phase, which could be due to its long half-life and reduced bioavailability. This may explain the decreased pharmacokinetic profiles of quetiapine in patients with MDD, GAD, and PD. Quetiapine was administered orally in patients with MDD, GAD, PD, and PD in a dose-escalation study [Quetiapine has been administered orally for the treatment of schizophrenia and bipolar disorder [
Seroquel is metabolized in the liver predominantly by cytochrome P450 (CYP) isoforms 2C9 (major route) and 3A4 (minor route) and is also responsible for the accumulation and clearance of quetiapine [
Seroquel has been administered orally for the treatment of schizophrenia and bipolar disorder [
Quetiapine is also metabolized to inactive metabolites after the liver clearance is reduced [
Quetiapine is metabolized in the liver to a metabolite that is excreted primarily by the kidneys, and is excreted in the urine mainly by the kidneys [
Quetiapine has a low affinity for CYP isoforms 2C9 (major route) and 3A4 (minor route) [
Therefore, it has been reported that quetiapine metabolism may be affected by its pharmacokinetic properties. In this study, the AUC, Cmax, and serum concentration-time profiles of quetiapine in patients with MDD, GAD, PD, and PD in the first dose of a once-daily administration (FDI) study were investigated.
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iaries�url.it?acy2=0Last updated on March 03, 2024
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Medicare CardNo MedicareDiscontinued in US on June 27, 2024
HealthylifeQuetiapine (25mg) 60 Extended Release TabletsHealthylife Global Pharmacy, an independently owned and operated pharmacy business, its manufactured by.
?? Please note that this product is?? not available in the US.?? This product is? not? currently available? in the US.?? We have? a? availability in the? US? and? are? awaiting availability of their own?delivery services in the US.
Seroquel (Quetiapine) can be purchased by calling +1-888-704-0408 and talking with a customer service representative, or by placing an online order at liferxpharmacy.com. Customer Support is also aided by using the chat feature. For additional information, visit the "How to Order" page on liferxpharmacy.com.
Seroquel (Quetiapine) is a medication that can only be purchased with a doctors prescription. While processing your order for the medication, it is necessary to get a valid prescription from your doctor The prescription can be scanned, emailed, or uploaded at liferxpharmacy.com or fax on +1-800-986-4751 Alternatively, if you like, we can even contact your doctor to obtain a valid prescription.
The maximum amount of Seroquel (Quetiapine) can be ordered at one time is a 90-day supply. The amount that can be ordered is dependent on the instructions and quantity mentioned on your medical prescription. Refilling alternate is always available for future needs.
It is a completely safe and secure choice to order your medicine from us. We function similarly alike any other traditional pharmacy, intending to serve safe and affordable prescription medicines. Our associated pharmacists are functional in many countries and are completely licensed and certified.
Seroquel (Quetiapine) is available in both generic and brand form. Generic medicines contain the same active components as brand-name pharmaceuticals have. They ensure and meet the same quality, strength, and purity standards in comparison to any other brand.
Yes. We deliver all around the United States and other major countries.
LifeRx pharmacy makes it simple to refill your medication. By going to your accounts reorder section, you can easily place a refill option available online. You may examine your prior orders and choose which prescriptions order needs to be refilled. To order a refill, you can also call us and chat with one of our customer service representatives. Our live chat is also one of the convenient ways to reach out to us while placing a refill order.
We do not automatically refill prescriptions as it might be the case where you may no longer be taking the same medicines or your doctor may have revised your dose, among other things. However, we do offer a helpful refill reminder service. Based on your prescription history, we may call or email you to let you know when the ideal time is to place a refill order.
Approval is now and time.Most patients have their original medicines prescribed by a doctor. However, some patients can more than once - some of them even develop other side effects. It is very important for patients with patients with different original medications (sales, use) to get patient identification affirmatively.
Patients with side effects (including those with severe anxiety, depression, Parkinson's disease or other disorders) have it filled by a legitimate source. These include a list of approved U. S. and Canadian brands and their manufacturer. Patients with side effects with a Canadian brand are prescribed a different dose of the original medication.
Seroquel is used to treat mental illness including schizophrenia, bipolar disorder, manic depression and depression (depression worsening). In addition to having mental health medicines, some patients have Seroquel (Quetiapine) prescribed for their schizophrenia, bipolar disorder, or other psychiatric medicines for which there are currently no licensed versions.
Sold and Supplied by Healthylife Pharmacy, this product is a prescription medicine. You can use this product to treat a condition that is not listed above. This product is only used for the treatment of. It is not.
Common side effects include:
Keep out of reach of children.
Do not use Seroquel XR (Quetiapine Fumarate) if:
Store at room temperature away from moisture and heat.
Seroquel XR (Quetiapine Fumarate) is not a controlled substance under the Controlled Substances Act (CSA).standby hours pass before your next shipment.
Seroquel XR (Quetiapine Fumarate) may cause muscle spasms, irregular heartbeat, or fainting. Your doctor will determine if these are severe or not.
Use caution when driving, operating machinery, or taking any other activity requiring alertness or coordination.
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